Thanks to the numerous donations that were made to them, the Carthusian Order was quickly at the head of a large domain in the region. Their riches, their influence, their reputation for being intercessor to God, their works of charity which redistributed a large share of the received donations to the needy persons of the region - all this could only cause jealousy and greed on the part of their noble neighbors.

Illustrations of this are the conflicts with the priorate of Saint Peter of Saint-Saturnin-du-Port (town now called Pont-Saint-Esprit).